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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NF2
All Species:
44.55
Human Site:
S315
Identified Species:
89.09
UniProt:
P35240
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35240
NP_000259.1
595
69690
S315
M
R
R
R
K
A
D
S
L
E
V
Q
Q
M
K
Chimpanzee
Pan troglodytes
XP_001136298
595
69538
S315
M
R
R
R
K
A
D
S
L
E
V
Q
Q
M
K
Rhesus Macaque
Macaca mulatta
XP_001106489
595
69702
S315
M
R
R
R
K
A
D
S
L
E
V
Q
Q
M
K
Dog
Lupus familis
XP_534729
596
69793
S315
M
R
R
R
K
A
D
S
L
E
V
Q
Q
M
K
Cat
Felis silvestris
Mouse
Mus musculus
P46662
596
69758
S315
M
R
R
R
K
A
D
S
L
E
V
Q
Q
M
K
Rat
Rattus norvegicus
Q63648
586
68693
S311
M
R
R
R
K
A
D
S
L
E
V
Q
Q
M
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521866
636
73533
P308
M
R
R
R
R
V
D
P
V
E
I
Q
H
M
K
Chicken
Gallus gallus
Q9PU45
583
68536
T299
M
R
R
R
K
P
D
T
I
E
V
Q
Q
M
K
Frog
Xenopus laevis
NP_001086957
585
68810
S315
M
R
R
R
K
A
D
S
L
E
V
Q
Q
M
K
Zebra Danio
Brachydanio rerio
NP_001122179
593
69546
S314
M
R
R
R
R
V
D
S
L
E
V
Q
Q
M
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24564
635
74474
T309
M
R
R
R
K
P
D
T
M
E
I
Q
Q
M
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781142
608
70697
S325
M
Q
R
R
R
A
D
S
M
E
V
Q
Q
M
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.4
99.8
99.5
N.A.
98.3
95.1
N.A.
61.7
44.8
86.8
82.5
N.A.
47.4
N.A.
N.A.
56.5
Protein Similarity:
100
97.6
99.8
99.5
N.A.
99.3
96.6
N.A.
76.5
65.5
92.7
91.2
N.A.
66.3
N.A.
N.A.
75.4
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
60
80
100
86.6
N.A.
73.3
N.A.
N.A.
80
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
80
93.3
100
93.3
N.A.
93.3
N.A.
N.A.
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
67
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
100
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
100
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
9
0
17
0
0
0
0
% I
% Lys:
0
0
0
0
75
0
0
0
0
0
0
0
0
0
100
% K
% Leu:
0
0
0
0
0
0
0
0
67
0
0
0
0
0
0
% L
% Met:
100
0
0
0
0
0
0
0
17
0
0
0
0
100
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
17
0
9
0
0
0
0
0
0
0
% P
% Gln:
0
9
0
0
0
0
0
0
0
0
0
100
92
0
0
% Q
% Arg:
0
92
100
100
25
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
75
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
17
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
17
0
0
9
0
84
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _